• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    “LOW-COST SINGLE-USE INJECTOR” This is an injection device (100, 200), which includes a safety guard (104, 204) and a housing (108, 208). The safety guard (104, 204) has a first end and a surface arranged on a second end of the same for contact with a patient's skin, and a protective flap (164, 240) extending from the same. The housing (108, 208) is slidably arranged in relation to the safety guard (104, 204) and includes a guide groove (172, 252) for engaging the protective flap (164, 240) to guide the movement of the housing (108, 208) in relation to the safety guard (104, 204). The guide groove (172, 252) has first (184, 256) and second (188, 260) axial parts and a substantially helical part (192, 264) that connects the first and second axial parts (184, 188, 256, 260). The device (100, 200) also includes a medicine container (120, 220) connected to the housing (108, 208) and which has a needle (124, 224) attached to it in communication with a medicine arranged inside the medicine container (120, 220). The medicine container (120, 220) is movable in relation to the safety guard (104, 204) from an initial position to an injection position, to a withdrawal position. The device (100, 200) additionally includes a biasing element (128, 228) that moves the medicine container (120, 220) away from the safety guard (104, 204) and an injector (112, 212) ) slidably arranged with respect to the medicine container (120, 220), to expel the medicine from the medicine container (120, 220).
    公开号:BR112013029579B1
    申请号:R112013029579-1
    申请日:2011-05-18
    公开日:2021-02-23
    发明作者:Michael Quinn
    申请人:Becton Dickinson And Company；
    IPC主号:
    专利说明:

    Field of invention
    [001] The present invention generally relates to an injection device for dispensing a drug and, more particularly, to a single-use, low-cost injection device. Fundamentals of the invention
    [002] Various injection devices are known in the art. Many such injection devices, however, require medical training for proper use. In addition, many such injection devices are expensive. Thus, there is a need to provide an intuitive low-cost injection device that can be used appropriately by untrained or minimally trained individuals for self-injection or injection into others. For example, such a necessary device could be used for inoculations in areas of the developing world, where medical care is difficult to obtain, or for a parent to inoculate a child. In addition, needles can be intimidating for some patients. Consequently, an injection device to hide the needle from the user is desirable, both before and after injection. Summary of the invention
    [003] One aspect of the present invention is to provide a single-use, low-cost injection device. Another aspect of the present invention is to provide an intuitive injection device that can be used appropriately by untrained or minimally trained individuals for self-injection or injection of others. Another aspect of the present invention is to provide an injection device in which the needle is concealed prior to injection and protected after injection.
    [004] The previously mentioned and / or other aspects of the present invention are achieved by providing an injection device, which includes a safety guard and a housing. The safety guard has a first end and a surface disposed at a second end thereof for contact with a patient's skin, and a protector flap that extends from it. The housing is slidably arranged in relation to the safety guard and includes a guide groove for engaging the guard flap to guide the movement of the housing in relation to the safety guard. The guide groove has first and second axial parts and a substantially helical part that connects the first and second axial parts. The device also includes a medicine container connected to the housing and which has a needle attached to it in communication with a medicine disposed within the medicine container. The medicine container is movable in relation to the safety guard from an initial position to an injection position, to a withdrawal position. The device additionally includes a propensity element that pushes the medicine container away from the safety guard and an injector element slidably arranged with respect to the medicine container, to expel the medicine from the medicine container.
    [005] The previously mentioned and / or other aspects of the present invention are also achieved by providing an injection device, which includes a safety guard that has a first end and a surface arranged at a second end thereof for contact with a patient's skin, and a medicine container slidably connected to the safety guard. The medicament container includes a needle attached to it in communication with a medicament disposed within the medicament container. The medicine container is movable in relation to the safety guard from an initial position to an injection position, to a withdrawal position. The device also includes an injector element that has a plunger and a plug disposed at a first end of the plunger, a propensity element that pushes the medicine container away from the safety guard, and a slidably arranged housing in relation to both the safety guard as well as the medicine container. The housing includes a swinging upper locking arm that selectively prevents displacement of the housing and plunger in relation to the medicine container. One of the upper locking arm and the safety guard includes a ramp and the rest of the upper locking arm and the safety guard includes a corresponding radial protrusion. Under the displacement of the medicine container from the initial position to the injection position in which the needle extends beyond the safety guard, the ramp comes into contact with the radial protuberance to radially displace a free end of the upper locking arm, to allow movement of the housing in relation to the medicine container.
    [006] The previously mentioned and / or other aspects of the present invention are also achieved by providing an injection device, which includes a safety protector that has a surface for contact with a patient's skin, a connected internal housing of sliding mode to the safety guard and which has a cam track with first and second part, a needle connector slidably connected to the inner housing to move from a first position to a second position in relation to it, and a needle with double end attached to the needle connector. The device also includes a medicine container for holding a medicine, slidably connected to the safety protector, a slidably disposable plug in the medicine container, a propensity element disposed within the safety protector and which provides the medicine container in a first direction, and a needle guard to selectively cover a first ex-needle tip, the needle guard that has at least one cam flap slidably engaged with the cam track. Moving the cam flap along the first part of the cam track moves the needle connector to the second position, piercing the plug with the needle.
    [007] The additional and / or other aspects and advantages of the present invention will be presented in part in the description that follows and, in part, will be evident from the description, or can be discovered by the practice of the invention. Brief description of the drawings
    [008] The additional and / or other aspects and advantages of the modalities of the invention will be more readily understood from the following detailed description, taken in conjunction with the attached drawings, in which: Figure 1 is a perspective view of a device injection according to an embodiment of the present invention; Figure 2 is a cross-sectional view of the device of Figure 1 in an initial state; Figure 3 is a perspective view of a safety guard for the device of Figure 1; Figure 4 is a perspective view of a housing for the device of Figure 1; Figure 5 is a cross-sectional view of the housing of Figure 4 taken along line 5-5 of Figure 4; Figures 6 to 8 are seen in cross section that illustrate the operation of the device of Figure 1; Figure 9 is a perspective view of the Figure 1 device in a safe post-injection state; Figure 10 is a perspective view of an injection device according to another embodiment of the present invention; Figure 11 is a cross-sectional view of the device of Figure 10 in an initial state; Figure 12 is a perspective view of a housing of the device of Figure 10; Figure 13 is a cross-sectional view of the housing taken along line 13-13 of Figure 12; Figure 14 is a cross-sectional view of the device of Figure 10 in an injection state; Figure 15 is a cross-sectional view of the device of Figure 10 following the injection of a drug; Figure 16 is a cross-sectional view of the Figure 10 device in a safe post-injection state; Figure 17 is a perspective view of an injection device according to another embodiment of the present invention; Figure 18 is a cross-sectional view of the device of Figure 17 taken along line 18-18 of Figure 17; Figure 19 is a partial cross-sectional view of an internal housing of the device of Figure 17; Figure 20 is a cross-sectional view of the device of Figure 17 with a needle-pierced plug; Figure 21 is a cross-sectional view of the device of Figure 17 with a needle guard removed; Figure 22 is a cross-sectional view of the device of Figure 17 with the needle positioned; Figure 23 is a cross-sectional view of the device of Figure 17 following the injection of a drug; Figure 24 is a cross-sectional view of the Figure 17 device in a safe post-injection state. Detailed description of the exemplifying modalities
    [009] Reference will now be made in detail to the modalities of the present invention, examples of which are illustrated in the accompanying drawings, where similar reference numbers refer to similar elements throughout this document. The descriptions of these modalities exemplify the present invention by referring to the drawings.
    [010] Figure 1 is a perspective view of an injection device 100 according to an embodiment of the present invention. The injection device 100 includes a safety guard 104, a housing 108 and an injector or injector button 112. The housing 108 is slidably connected with the safety guard 104. The injection device 100 also includes a needle guard removable 116.
    [011] Figure 2 is a cross-sectional view illustrating the injection device 100 in an initial state. As shown in Figure 2, the injection device 100 also includes a medicine container 120 with the needle 124 attached to it and a bias element 128, such as a spring 128. According to one embodiment, the medicine container 120 includes a flexible blister 132 with a connector 136 to hold the needle 124. The needle 124 is fluidly connected to the flexible blister 132 through the connector 136. An example of such a medicine container is shown in the document under no. U.S. 4,955,871 to Thomas, which is hereby incorporated by reference in its entirety. According to one embodiment, the medication container 120 is fixedly connected to housing 108. According to another embodiment (not shown), the medication container includes a double-ended needle that pierces a valve membrane when the protector needle is pushed back. This configuration acts as an anti-reuse and anti-tamper feature.
    [012] Figure 2 also illustrates the injection button 112 includes an inner slot 140 axially aligned with the flexible blister 132. In addition, Figure 2 illustrates that the housing 108 includes inner and outer walls 144 and 148. The propensity element 128 is disposed between the inner and outer wall 144 and 148 and the injector 112 and the medicine container 120 are arranged radially within the inner wall 144. The injection button 112 is slidably arranged in relation to the medicine container 120 and the wall internal 144.
    [013] The inner wall 144 has a pair of holders, which includes an initial holder 152 and a locking holder 156. According to one embodiment, holders 152 and 156 are circumferential recesses in an internal surface of the inner wall 144. according to another modality, holders 152 and 156 consist of discontinuous circumferential recesses arranged on the inner surface of the inner wall 144. The injection button 112 includes a projection of button 158 disposed on a distal end thereof and which has a shape that corresponds to the holders 152 and 156. The button projection 158 and the initial holder 152 interact to prevent proximal movement of the injection button 112 in relation to the housing 108 subsequent to the button projection 158 that engages the initial holder 152. Similarly, as discussed in more detail below , the button projection 158 and the locking catch 156 interact to prevent the proximal movement of the injection button 112 in relation to the housing 108 following the projection of button 158 that engages locking holder 156.
    [014] As shown in Figures 2 and 3, the safety guard 104 is substantially cylindrical and has a depth stop 160 to limit the penetration of needle 124 into a patient's skin. Safety guard 104 also includes a guard flap 164 that protrudes radially from a flange 168 disposed at a proximal end of safety guard 104. Flange 168 provides a support surface for a distal end of the prop element 128 and the guard flap 164 interacts with a guide groove 172 in the housing 108 to guide the movement of the housing 108 with respect to the safety guard 104. The distal end of the safety guard 104 defines a surface 170 for contact with a skin of the patient.
    [015] As shown in Figure 4, housing 108 includes an upper swing arm 176 and a lower swing arm 180. As described in more detail below, the upper swing arm 176 and the lower swing arm 180 are guide groove locking elements 172. Figure 5 is a cross-sectional view of housing 108 taken along line 5-5 of Figure 4. As shown in Figure 5, guide groove 172 includes substantially first and second parts axial parts 184 and 188 and a substantially helical part 192 that connects the first and second axial parts 184 and 188. According to one embodiment, for molding purposes, the substantially helical part 192 penetrates into housing 108. As discussed in greater detail below, also shown in Figure 5, the upper flexible arm 176 includes a ramp 194 disposed at the free end of an inner side thereof. In addition, the lower flexible arm 180 includes a ramp hook 196.
    [016] Figures 6 to 8 are seen in cross section illustrating the operation of the injection device 100. To operate the device, a user first removes the needle guard 116 and places the surface 170 of the safety guard 104 on a skin of patient 194. Subsequently, the user presses the injector button 112 to move the medication container to an injection position. The force required to compress the propensity element 128 and the force required to penetrate the user's skin with the needle 124 are less than that required to move the button projection 158 from the initial stop 152. Consequently, when the user presses the injector button 112, the housing 108 slides distally with respect to the safety guard 104 and the needle 124 penetrates the skin of the user 198, stopping at a predetermined depth when the connector 136 of the medicine container 120 comes into contact with the depth limiter 160, as shown in Figure 6.
    [017] During this distal displacement of the housing 108 in relation to the safety guard 104, the guard flap 164 engages the first axial part 184 of the guide groove 172 and moves proximally to it. In other words, the engagement of the guard flap 164 and the first axial part 184 forces the displacement of the housing 108 with respect to the safety guard 104 to be axial and prevents the rotation of the housing 108 with respect to the safety guard 104. As as connector 136 approaches depth limiter 160, guard flap 164 passes ramp 194 and radially displaces the free end of upper flexible arm 176. As connector 136 engages depth limiter 160, protector flap 164 completes the passage of the ramp 194 and reaches the proximal end of the first axial part 184. After the protector flap 164 passes the ramp 194, the free end of the upper flexible arm 176 contracts to form a part of the helical part 192 of the groove guide 172 and to prevent subsequent axial movement of the guard flap 164 in the first axial part 184.
    [018] With reference to Figure 7, as the user continues to press the injection button 112, the button projection 158 moves from the initial stop 152 and the injection button 112 moves distally in relation to the inner wall 144 and to the medicine container 120 until the button projection 158 engages the locking holder 156. During this distal displacement of the injection button, the walls of the inner slot 140 engage and compress the flexible blister 132 and expel the medicine from the flexible blister 132 in the patient. Since the button projection 158 engages the locking holder 156 (which defines an injection state), the corresponding shapes of the same prevent the subsequent proximal displacement of the injection button 112 in relation to the housing 108. Furthermore, since the medication is injected, the proximal end of the injection button 112 is arranged sufficiently close to the proximal end of the housing 108 that a user cannot have firm contact with the injection button 112 to attempt the proximal displacement of the injection button 112. According to one embodiment, once the drug is injected, the proximal end of the injection button 112 is substantially aligned with the proximal end of the housing 108.
    [019] Subsequent to the medication injection, the user releases the injection button 112 and the propensity element 128 moves the housing 108 proximally (as well as the medicine container 120 and the injection button 112) in relation to the safety guard 104 thus moving the medication container 120 (and the needle 124) to a withdrawal position. Due to the fact that the guard flap 164 engages the helical part 192 of the guide groove 172, during a first part of the proximal displacement, the housing 108 rotates until the guard flap 164 reaches the proximal end of the second axial part 188. At this time, the bias element 128 continues to proximally displace the housing 108 and the engagement of the guard flap 164 in the second axial part 188 forces the proximal displacement to be axial. As the housing 108 approaches the completion of its proximal displacement, the protective flap 164 passes from the ramp hook 196 of the lower flexible arm 180 and radially displaces the free end of the lower flexible arm 180. And as the housing 108 completes its proximal displacement (shown in Figures 8 and 9), the guard flap 164 completes the passage of the ramp hook 196 and reaches the distal end of the second axial part 188. After the guard flap 164 passes the ramp hook 196 , the free end of the lower flexible arm 180 contracts to prevent subsequent axial movement of the protector flap 164 in the second axial part 188. In other words, the free end of the lower flexible arm 180 locks the protector flap 164 and prevents displacement subsequent arrangement of housing 108 with respect to safety guard 104, thereby securing the injection device 100 in a safe post-injection state.
    [020] Figure 10 is a perspective view of an injection device 200 according to another embodiment of the present invention and Figure 11 is a cross-sectional view of the injection device 200. As shown in Figure 10, the injection device injection 200 includes a safety guard 204 and a housing 208. Although not shown, the injection device 200 also includes a removable needle guard. The housing 208 slidily connects to the safety guard 204. As shown in Figure 11, the injection device 200 also includes an injector element 212 (which includes a plunger 214 and a plug 216) that slidily connects with a medicament container 220, which has a needle 224 affixed to a distal end thereof. In addition, the injection device 200 includes a propensity element 228 that extends the medicine container 220 proximally away from the safety guard 204. The needle 224 communicates with a medicine disposed within the medicine container 220. Similar to the medicine container 120, the medicine container 220 is movable relative to the safety guard 204 from an initial position (shown in Figure 11), to an injection position (shown in Figure 14), to a withdrawal position (shown in Figure 16). In addition, the safety guard 204 (which has a depth stop 232, a flange 236 and a guard flap 240) is substantially similar to the safety guard 104 described earlier. Consequently, the additional detailed description of the safety guard is omitted for the sake of brevity.
    [021] Figure 12 is a perspective view of housing 208 that illustrates that, similar to housing 108, housing 208 includes an upper flexible arm 244 and a lower flexible arm 248. Figure 13 is a cross-sectional view of the housing 208 taken along line 13-13 of Figure 12, and illustrates that, also similar to housing 108, housing 208 includes a guide groove 252 that includes first and second axial parts 256 and 260, and a substantially helical part 264 that connects the first and second axial parts 256 and 260. Additionally, the upper flexible arm 244 is disposed on the first axial part 256 and the lower flexible arm 248 is disposed on the second axial part 260. Additionally, the upper flexible arm 244 includes a ramp 268 disposed at a free end thereof and the lower flexible arm 248 includes a ramp hook 272 disposed at a free end thereof. Ramp 268 and ramp hook 272 function substantially similar to ramp 194 and ramp 196 described earlier. Consequently, the additional detailed description of the ramp 268 and the ramp hook 272 is omitted for the sake of brevity.
    [022] Unlike housing 108, however, the upper flexible arm 244 includes a locking protrusion 276 at a proximal end thereof to selectively prevent displacement of housing 208 and plunger 214 from medicine container 220. The upper flexible arm 244 also has an unlocking ramp 280 disposed thereon. As described in more detail below, the unlocking ramp 280 interacts with the guard flap 240 to radially displace the free end of the upper flexible arm 244 to allow movement of the housing 208 in relation to the medication container 220. According to a As shown in Figure 13, the upper flexible arm 244 has two parts. The locking protrusion 276 is arranged in a first part, and the ramp 268 and the unlocking ramp 280 are arranged in a second part, which also includes the first axial part 256 of the guide groove 252.
    [023] With reference again to Figure 11, in the initial state, the locking protuberance 276 engages a radial flange 284 disposed at a proximal end of the medication container 220. This engagement prevents the displacement of housing 208 and plunger 214 from the medicine container 220. Thus, when a user applies force to the proximal end of housing 208, radial flange 284 compresses propensity element 228, and housing 208, injector element 212, and medicine container 220 move apart. as a unit with respect to safety guard 204 until the medicine container 220 reaches the depth stop 232, which consists of an injection state shown in Figure 14. This displacement of the medicine container 220 also leads to needle 224 to pierce the patient's skin.
    [024] As shown in Figure 14, as the housing 208 and the medicine container 220 reach the injection state, the guard flap 240 moves in the first axial part 256 and engages the unlocking ramp 280 to radially displace a free end of the upper flexible arm 244, thus disengaging the locking protrusion 276 from the radial flange 284. Consequently, due to the fact that the locking protrusion 276 no longer engages the radial flange 284, the housing 208 (as well as the plug 216 and the plunger 214, which contacts the housing 208) is displaceable with respect to the medicine container 220. Thus, as the user continues to apply force to the proximal end of the housing 208, as shown in 15, the housing 208 and the injector element 212 move distally from the medicine container 220, expelling the medicine from the medicine container 220.
    [025] Additionally, during this distal displacement of the housing 208 in relation to the safety guard 204, the guard flap 240 continues to move proximally to the first axial part 256 of the guide groove 252. In other words, the engagement of the guard protector flap 240 and the first axial part 256 forces the displacement of housing 208 with respect to safety guard 204 to be axial and prevents rotation of housing 208 with respect to safety guard 204. As the housing approaches the end distal from its course and the medicine container 220 approaches the depth stop 232, the protective flap 240 passes from the ramp 268 and radially displaces the free end of the upper flexible arm 244. And as the medicine container 220 engages the depth limiter 232, protector flap 240 completes the passage of the ramp 268 and reaches the proximal end of the first axial part 256. After the protector flap 240 passes the ramp 268, the free end of the upper flexible arm 244 contracts to form a part of the helical part 264 of the guide groove 252 and to prevent subsequent axial movement of the guard flap 240 in the first axial part 256.
    [026] Similar to the injection device 100 described above, subsequent to the injection of the medicine, the user releases housing 208 and the propensity element 228 moves the housing 208 proximally (as well as the medicine container 220 and the injector element 212) in relative to the safety guard 204, thus moving the medicine container 220 (and the needle 224) to a withdrawal position. Due to the fact that the guard flap 240 engages the helical part 264 of the guide groove 252, during a first part of the proximal displacement, the housing 208 rotates until the guard flap 240 reaches the proximal end of the second axial part 260. At this time, the bias element 228 continues to proximally move the housing 208 and the engagement of the guard flap 240 in the second axial part 260 forces the proximal displacement of the housing 208 to be axial. As the housing 208 approaches the completion of its proximal displacement, the guard flap 240 passes the ramp hook 272 of the lower flexible arm 248 and radially displaces the free end of the lower flexible arm 248. And as the housing 208 completes its proximal displacement (shown in Figure 16), the guard flap 240 completes the passage of the ramp hook 272 and reaches the distal end of the second axial part 260. After the guard flap 240 passes the ramp hook 272 , the free end of the lower flexible arm 248 contracts to prevent subsequent axial movement of the protector flap 240 in the second axial part 260. In other words, the free end of the lower flexible arm 248 locks the protector flap 240 and prevents displacement subsequent arrangement of housing 208 relative to safety guard 204, thereby securing the injection device 200 in a safe post-injection state.
    [027] Figure 17 is a perspective view of an injection device 300 in an initial state and Figure 18 is a cross-sectional view of the device 300. As shown in Figures 17 and 18, the injection device 300 includes a safety guard 304 with a surface 306 for contact with a patient's skin arranged at a distal end thereof, a medicine container 308 slidably connected to safety guard 304, an internal housing 312 slidably connected to the safety guard security 304, and a needle guard 316 to selectively cover a distal end of a needle 324. The medicine container 308 can be made, for example, of glass or plastic. According to one embodiment, the safety guard 304 includes a pair of locking tabs 318, which are radially extended inwardly. The injection device 300 also includes a needle connector 320 slidably connected to the internal housing 312. The double-ended needle 324 is attached to the needle connector 320. The injection device 300 additionally includes a bias element 328 arranged inside the security guard 304 and which proximally extends the medicine cartridge 308, and a plug 332 slidably arranged on the medicine cartridge 308. According to one embodiment, the internal housing 312 has a burr 334 at the proximal end of the same with a corresponding recess 338 at the distal end of the plug 332, to secure the plug 332 to the internal housing 312.
    [028] The needle connector 320 has a radial protrusion 336 arranged at a proximal end thereof and the internal housing 312 includes a pair of holders or receiving grooves 340 (shown in Figure 19) that correspond to the radial protrusion 336. According to one embodiment, the radial protrusion 336 and the receiving grooves 340 are circumferential. As discussed in greater detail below, needle connector 320 is movable from a first position, in which the radial protrusion 336 is arranged distally between the receiving grooves 340, to a second position, in which the radial protrusion 336 it is arranged proximally between the receiving slots 340.
    [029] According to one embodiment, the inner housing 312 also includes a pair of cam tracks 344 that slide a pair of cam tabs 348 from the needle guard 316. As shown in Figure 19, each cam track 344 includes a substantially helical first part 352 and a substantially linear second part 356. As the user rotates the needle guard 316, the cam flaps 348 move along the helical parts 352 until they reach the end of the helical parts 352 ( and the beginning of the linear parts 356). This rotation of the needle guard 316 proximally moves the needle connector 320 from the first position to the second position and pierces the plug 332 with the proximal end of the needle 324, as shown in Figure 20.
    [030] Subsequently, with the cam tabs 348 arranged in the linear parts 356, the user distally moves the needle guard 316 to remove it from the injection device 300. The injection device 300, as shown in Figure 21, is now ready for injection.
    [031] The user then places the injection device 300 so that the surface 306 of the safety guard 304 contacts the user's skin and presses down on the medicine container 308, compressing the propensity element 328 According to one embodiment, the combination of forces from the drug back pressure in the medicine container 308 and the friction between the plug 332 and the medicine container 308 is greater than the combination of the force force from the propensity element 328 and the force required for needle 324 to pierce the patient's skin, so that, under the distal displacement of the medicine container 308, the needle 324 perforates the patient's skin prior to dispensing the medicine. This downward pressure on the medication container 308 drives the needle 324 into the patient's skin until the inner housing 312 contacts the patient's skin, as shown in Figure 22.
    [032] Once the inner housing 312 comes into contact with the patient's skin, continued downward pressure on the medicine container 308 expels the medicine from the medicine container 308 through needle 324 until the medicine container 308 reaches the end of its course, as shown in Figure 23. According to one embodiment, at the end of the course of the medicine container, the proximal end of the medicine container 308 is substantially aligned with the proximal end of the safety guard 304.
    [033] Subsequent to the medication injection, the user releases the medication container 308, and the force of the propensity element 328 proximally displaces the medication container 308 (as well as the internal housing 312 and the needle 324). Since the distal end of the inner housing 312 passes the locking tabs 318, the locking tabs 318 move rapidly radially inward due to their propensity radially inward. In this position, as shown in Figure 24, the locking tabs 318 prevent subsequent distal displacement of the inner housing 312 beyond it and thus prevent the reuse of the injection device 300.
    [034] The modalities of the present invention are easy to use and can hide the needle before injection, thus making it less intimidating for users who might not be used to injections. Additionally, in the embodiments of the present invention, the insertion of the needle and the course of the injection can be achieved in a single movement. In addition, the needle can be automatically protected once the device is removed from the skin, in the embodiments of the present invention. In addition, the compact size and low number of components of the embodiments of the present invention can reduce manufacturing costs, as well as transportation and storage costs.
    [035] In comparison with traditional autoinjectors, the compact size and low number of components of the modalities of the present invention can be achieved by eliminating some of the higher order characteristics of such autoinjectors. For example, the embodiments of the present invention do not require automatic spring-activated pressure mechanisms that make an auto-injector "automatic". On the contrary, users can apply the necessary force. To ensure that users apply a minimum required force and also to ensure rapid needle insertion, the embodiments of the present invention may have a force-based stopper that the user must overcome before the injection can begin. Once the holder is overcome, the needle assembly fits into the skin and then the injection begins. By eliminating the requirement for an automatic spring-loaded automatic pressure mechanism, other features can also be eliminated, such as an activation button, and a spring-activated safety device that only allows the injector to be triggered once is pushed against an object.
    [036] Although only a few exemplary embodiments of the present invention have been described in detail above, those skilled in the art will readily understand that many modifications are possible in the exemplifying embodiments without departing from the material point of view of the new instructions and advantages of this invention. Consequently, all such modifications are intended to be included in the scope of the appended claims and equivalents thereof.
    权利要求:
    Claims (20)
    [0001]
    1. Injection device (100, 200) comprising: a safety guard (104, 204) having a first end and a surface disposed at a second end thereof to contact a patient's skin, the safety guard (104, 204) having a protector tab (164, 240) extending therefrom; a housing (108, 208) slidably arranged with respect to the safety guard (104, 204), the housing (108, 208) including a guide groove (172, 252) for engaging the guard flap (164, 240 ) to guide movement of the housing (108, 208) in relation to the safety guard (104, 204), the guide groove (172, 252) having first and second axial parts (184, 188, 256, 260) and a part helical (192, 264) connecting the first and second axial parts (184, 188, 256, 260); a medicine container (120, 220) connected to the housing (108, 208) and having a needle (124, 224) attached to it in communication with a medicine disposed within the medicine container (120, 220), in which the medicine container (120, 220) is movable in relation to the safety guard (104, 204) from an initial position to an injection position, to a withdrawal position; a bias element (128, 228) tending the medicine container (120, 220) away from the safety guard (104, 204); and an injector element (122, 212) slidably arranged with respect to the medicine container (120, 220), to expel the medicine from the medicine container (120, 220); CHARACTERIZED by the fact that the housing (108, 208) comprises a swinging upper flexible arm (176, 244) and a swinging lower flexible arm (180, 248) being locking elements of the guide groove (172, 252), wherein the swinging upper flexible arm (176, 244) is arranged over the first axial part (184, 256) of the guide groove (172, 252) and the swinging lower flexible arm (180, 248) is arranged on the second axial part (188, 260) of the guide groove (172, 252).
    [0002]
    2. Injection device (100, 200) according to claim 1, CHARACTERIZED by the fact that the safety guard (104, 204) includes a depth stop (160, 232) to limit needle penetration (124, 224) on a patient's skin.
    [0003]
    3. Injection device (100, 200), according to claim 1, CHARACTERIZED by the fact that subsequent to the protective flap (164, 240) passing the respective free ends of it, the upper flexible arm in balance (176, 244 ) and the lower swinging flexible arm (180, 248) prevent reverse displacement of the guard flap (164, 240) along the corresponding axial parts of the guide groove (172, 252).
    [0004]
    4. Injection device (100, 200), according to claim 3, CHARACTERIZED by the fact that the upper flexible arm (176, 244) comprises a ramp (194, 268) at a free end thereof; wherein as the guard flap (164, 240) passes the ramp (194, 268), the guard flap (164, 240) radially displaces the free end of the upper locking arm; and and subsequent to the guard flap (164, 240) passing the ramp (194, 268), the free end contracts to form a part of the helical part (192, 264) of the guide groove (172, 252).
    [0005]
    5. Injection device (100, 200), according to claim 3, CHARACTERIZED by the fact that the lower flexible arm (180, 248) comprises a ramp hook (196, 272) at a free end of it, in that as the bias element (128, 228) completes the displacement of the medicine container (120, 220) to the withdrawal position, the protector flap (164, 240) moves in the second axial part (188, 260 ) from the guide groove (172, 252) and passes the ramp hook (196, 272), radially displacing the free end of the lower locking arm; and where after the guard flap (164, 240) passes the ramp hook (196, 272), the free end of the lower locking arm contracts to prevent displacement of the housing (108, 208) in relation to the safety guard security (104, 204).
    [0006]
    6. Injection device (100, 200) according to claim 1, CHARACTERIZED by the fact that when the needle (124, 224) reaches a predetermined injection depth, the protector tab (164, 240) engages the part helical (192, 264) of the guide groove (172, 252); and when the injector element is subsequently released (122, 212), as the propensity element (128, 228) moves the housing (108, 208) and the medicine container (120, 220) away from the (104, 204), the housing (108, 208) rotates due to the engagement of the guard flap (164, 240) on the helical part (192, 264) of the guide groove (172, 252).
    [0007]
    7. Injection device (100, 200) according to claim 1, CHARACTERIZED by the fact that the medicine container (120, 220) is fixedly connected with the housing (108, 208): the housing (108 , 208) includes an inner wall (144) and an outer wall (148); the propensity element (128, 228) is arranged between the inner and outer walls (144, 148); and the medicament container (120, 220) is disposed radially into the inner wall (144).
    [0008]
    8. Injection device (100, 200), according to claim 7, CHARACTERIZED by the fact that: the medication container (120, 220) comprises a flexible blister (132); the injector element (122, 212) comprises an injection button (112) having an internal slot (140) axially aligned with the flexible blister (132); and as the injection button (112) is pressed, the walls of the internal slot (140) compress the flexible blister (132) to expel the medicine from the medicine container (120, 220).
    [0009]
    9. Injection device (100, 200), according to claim 7, CHARACTERIZED by the fact that one of the injector element (122, 212) and the inner wall (144) has a radial protrusion (158) and the other remaining between the injector element (122, 212) and the inner wall (144) has a pair of grooves (152, 156) to selectively retain the radial protuberance (158) and prevent proximal translation of the injector element (122, 212) in addition to the same; and a first groove among the groove pair (152, 156) corresponds to an initial state and the remainder of the groove pair (152, 156) corresponds to an injected state.
    [0010]
    10. Injection device (100, 200), according to claim 3, CHARACTERIZED by the fact that the medicine container (120, 220) is slidably connected with the housing (108, 208) and the safety guard (104, 204); wherein the injector element (122, 212) comprises a plunger (214) and a plug (216) arranged at a first end of the plunger (214), and the housing (108, 208) comes into contact with a second end of the plunger (214) opposite the first end; and in which displacement of the housing (108, 208) in relation to the medicine container (120, 220) and the safety guard (104, 204) expels the medicine from the medicine container (120, 220).
    [0011]
    11. Injection device (100, 200), according to claim 10, CHARACTERIZED by the fact that at the end of the housing stroke (108, 208) to expel medicine from the medicine container (120, 220), a flap of protector (240) arranged on the protector engages the helical part (264) of the guide groove (252); and when releasing the housing (108, 208), the propensity element (128, 228) moves the medicine container (120, 220) and the housing (108, 208) away from the safety guard (104, 204) , rotating the housing (108, 208) due to the engagement of the protector flap (240) on the helical part (264).
    [0012]
    12. Injection device (100, 200), according to claim 10, CHARACTERIZED by the fact that the upper flexible arm (176, 244) comprises a locking protuberance (276) selectively preventing displacement of the housing (108, 208) and the plunger (214) in relation to the medication container (120, 220); wherein one of the upper flexible arm and the safety guard (104, 204) comprises an unlocking ramp (280) and the rest of the upper flexible arm (176, 244) and the safety guard (104, 204) comprises a radial protuberance (240); and in which when the medicine container (120, 220) is moved from the initial position to the injection position in which the needle (124, 224) extends beyond the safety guard (104, 204), the unlocking (280) contacts the radial protrusion (240) to radially displace a free end of the upper flexible arm, to allow movement of the housing (108, 208) in relation to the medication container (120, 220).
    [0013]
    13. Injection device (200) comprising: a safety guard (204) having a first end and a surface disposed at a second end thereof to contact a patient's skin; a medicine container (220) slidably connected to the safety guard (204), the medicine container (220) including a needle (224) attached to it in communication with a medicine disposed within the medicine container (220), wherein the medicine container (220) is displaceable relative to the safety guard (204) from an initial position to an injection position, to a withdrawal position; an injector element (212) comprising a plunger (214) and a plug (216) arranged at a first end of the plunger; a bias element (228) tending the medicine container (220) away from the safety guard (204); and a housing (208) slidably arranged in relation to both the safety guard (204) and the medicine container (220), in which the housing (208) includes an upper flexible arm (244) selectively preventing displacement of the housing ( 208) and the plunger (214) relative to the medication container (220); CHARACTERIZED by the fact that: one of the upper flexible arm (244) and the safety guard (204) comprises a ramp (268) and the remainder between the upper flexible arm (244) and the safety guard (204) comprises a corresponding radial protuberance (240); when the medicine container (220) is moved from the initial position to the injection position in which the needle (224) extends beyond the safety guard (204), the ramp (268) comes into contact with the radial protuberance (240) to radially displace a free end of the upper flexible arm (244), to allow movement of the housing (208) in relation to the medication container (220); the housing (208) contacts a second end of the plunger (214) opposite the first end; and subsequent to the displacement of the medicine container (220) from the initial position to the injection position, displacement of the housing (208) in relation to the medicine container (220) and the safety guard (204) expels the medicine from the container of medication (220).
    [0014]
    Injection device (200) according to claim 13, CHARACTERIZED by the fact that the safety guard (204) includes a depth limiter to limit penetration of the needle (224) into a patient's skin.
    [0015]
    15. Injection device (300) FEATURED by the fact that it comprises: a safety protector (304) having a surface to contact a patient's skin; an internal housing (312) slidably connected to the safety guard (304) and having a cam track (344) with first and second parts (352, 356); a needle connector (320) slidably connected to the inner housing (312) to move from a first position to a second position in relation thereto; a double-ended needle (324) attached to the needle connector (320); a medicine container (308) for holding a medicine, slidably connected to the safety guard (304); a plug (332) slidably disposed on the medicament container (308); a bias element (328) disposed within the safety guard (304) and biasing the medicine container (308) in a first direction; and a needle guard (316) to selectively cover a first end of the needle (324), the needle guard (316) having at least one cam flap (348) slidably engaged with the cam track (344); wherein displacement of the cam flap (348) along the first part of the cam track (344) moves the needle connector (320) to the second position, piercing the plug (332) with the needle (324).
    [0016]
    16. Injection device (300) according to claim 15, CHARACTERIZED by the fact that displacement of the cam flaps (348) along the second part of the cam track (344) removes the needle guard (316), preparing the device (300) for injection.
    [0017]
    Injection device (300) according to claim 15, CHARACTERIZED by the fact that the first part of the cam track (344) is helical and the second part of the cam track (344) is linear.
    [0018]
    18. Injection device (300) according to claim 16, CHARACTERIZED by the fact that the combination of a counter pressure of the medicine container (308) and a friction between the plug (332) and the medicine container (308) is greater than the combination of a force from the propensity element (328) and a force required for the needle (324) to pierce a patient's skin, so that when the medicine container (308) is displaced in towards the patient's skin, the needle (324) punctures the patient's skin before dispensing the medication.
    [0019]
    19. Injection device (300), according to claim 18, CHARACTERIZED by the fact that it additionally comprises at least one locking flap (318) propelled towards the implantation, in which subsequent the completion of the injection, when the release of the medicine container (308), the bias element (328) moves the medicine container (308) and the inner housing (312) in the first direction beyond the locking tab (318), and the locking tab (318) is implanted to avoid distal displacement of the internal housing (312) beyond the same in a second direction opposite to the first direction.
    [0020]
    20. Injection device (100) comprising: a safety guard (104) having a first end and a surface disposed at a second end thereof to contact a patient's skin, the safety guard (104) having a safety flap. protector (164) extending from it; a housing (108) slidably arranged in relation to the safety guard (104), the housing (108) including a guide groove (172) for engaging the guard flap (164) to guide movement of the housing (108) in with respect to the safety guard (104), the guide groove (172) having first and second axial parts (184, 188) and a helical part (192) connecting the first and second axial parts (184, 188); a medicine container (120) connected to the housing (108) and having a needle (124) attached to it in communication with a medicine disposed within the medicine container (120), in which the medicine container (120) is movable in relation to the safety guard (104) from an initial position to an injection position, to a withdrawal position; a bias element (128) tending the medicine container (120) away from the safety guard (104); and an injector element (122) slidably arranged with respect to the medication container (120), to expel the medication from the medication container (120); CHARACTERIZED by the fact that: the medicine container (120) is fixedly connected with the housing (108); the housing (108) includes an inner wall (144) and an outer wall (148); the propensity element (128) is disposed between the inner and outer walls (144, 148); the medicament container (120) is disposed radially into the inner wall (144); one between the injector element (122) and the inner wall (144) has a radial protrusion (158) and the rest between the injector element (122) and the inner wall (144) has a pair of grooves (152, 156) for selectively retain the radial protrusion (158) and avoid proximal translation of the injector element (122) beyond it; and a first groove among the groove pair (152, 156) corresponds to an initial state and the remainder of the groove pair (152, 156) corresponds to an injected state.
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    同族专利:
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    US9656027B2|2017-05-23|
    WO2012158135A1|2012-11-22|
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    CA3005126C|2019-12-24|
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    CA2978589A1|2012-11-22|
    EP2709694A4|2014-12-03|
    CA2978588C|2019-12-31|
    CN103619381A|2014-03-05|
    JP5833229B2|2015-12-16|
    MX2013013309A|2014-02-27|
    MX370263B|2019-12-09|
    CA2836232C|2019-03-12|
    JP2014516687A|2014-07-17|
    ES2674180T3|2018-06-27|
    EP2709694A1|2014-03-26|
    US20140088512A1|2014-03-27|
    EP2942072A1|2015-11-11|
    CA2836232A1|2012-11-22|
    MX346965B|2017-04-07|
    CN106039478A|2016-10-26|
    EP2709694B1|2018-03-21|
    DK2709694T3|2018-06-25|
    CA2978589C|2019-10-01|
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    法律状态:
    2018-12-26| B06F| Objections, documents and/or translations needed after an examination request according art. 34 industrial property law|
    2019-08-27| B06U| Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure|
    2020-06-09| B07A| Technical examination (opinion): publication of technical examination (opinion)|
    2020-12-08| B09A| Decision: intention to grant|
    2021-02-23| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/05/2011, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    PCT/US2011/000876|WO2012158135A1|2011-05-18|2011-05-18|Single-use injector of low cost|
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